2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester - Names and Identifiers
Name | tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate
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Synonyms | 2-Boc-2,7-diazaspiro[4.5]... 2,7-Diazaspiro[4.5]decan-1-on 2,7-diazaspiro[4.5]decan-1-one 2-Boc-2,7-diazaspiro[4.5]decane 2-Boc-2,7-diazaspiro[4.5]decane oxalate tert-Butyl-2,7-diazaspiro[4.5]decan-2-carboxylate tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate tert-butyl 2,7-diazaspiro[4,5]decane-2-carboxylate TERT-BUTYL 2,7-DIAZASPIRO[4.5]DECANE-2-CARBOXYLATE 2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester 2,8-Diaza-Spiro[4.5]Decane-2-Carboxylic Acid Tert-Butyl Ester 2,7-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-diMethylethyl ester
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CAS | 852339-03-8 885268-42-8 887118-43-6
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InChI | InChI=1/C8H14N2O/c11-7-8(3-5-10-7)2-1-4-9-6-8/h9H,1-6H2,(H,10,11) |
2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester - Physico-chemical Properties
Molecular Formula | C13H24N2O2
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Molar Mass | 240.34 |
Density | 1.07 |
Boling Point | 337℃ |
Flash Point | 158℃ |
Vapor Presure | 2.27E-05mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.533 |
2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester - Risk and Safety
Risk Codes | 52 - Harmful to aquatic organisms
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2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester - Introduction
Nature:
-Appearance: tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is a colorless and transparent liquid.
-Molecular formula: C12H23N3O2
-Molecular weight: 241.33g/mol
-Melting point:-65 ℃
-Boiling point: 230 ℃
-Density: approx. 0.951g/cm³
Use:
- tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate are mainly used as reagents and intermediates in organic synthesis.
-It can participate in a variety of organic reactions, such as esterification, reduction and oxidation of carbonyl compounds, etc. It also has applications in drug synthesis and the synthesis of chiral drugs.
Preparation Method:
- tert-butyl 2,7-diazaspiro[4.5] The preparation of decane-2-carboxylate can be achieved by a variety of methods. One of the commonly used methods is the reaction of 2,7-diazaspiro [4.5] decane-2-methanol with tert-butyric acid chloride to produce the corresponding esterification product. Thereafter, the target product is selectively tert-butyl-protected under appropriate conditions.
Safety Information:
- tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate should avoid inhalation, contact with skin and eyes.
-Wear appropriate protective equipment such as goggles and gloves when using.
-It should be operated in a well-ventilated place and avoid contact with fire or high temperature.
-In case of inhalation or contact, immediately go to a fresh air or rinse with water and seek medical attention immediately.
Please note that before performing any laboratory operations, please make sure that you have the correct operating skills and safety knowledge, and follow the relevant safety operating procedures.
Last Update:2024-04-09 15:18:00